Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19

https://doi.org/10.1101/2020.04.26.20081059

In a multicenter prospective observational study, a total of 197 patients completed chloroquine treatment. The median time to achieve an undetectable viral RNA was shorter in chloroquine than in non-chloroquine. The duration of fever is shorter in chloroquine. No serious adverse events were observed in the chloroquine group. Patients treated with half dose experienced lower rate of adverse events than with the full dose.

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