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| Knowhow offering | |
| Title | A cost effective process for the preparation of phosphorous ligands and their precursors (valuable intermediates in organic synthesis) |
| Knowhow is available for | A cost effective, one reactor synthesis process for aryl phosphonates/phosphinates/phosphine oxides which are important ligand useful in organic synthesis |
| Summary | Aryl and hetero-aryl phosphorous compounds including phosphonates, phosphinites and phosphine oxides are valuable intermediates in organic synthesis and find applications in polymer synthesis, medicinal chemistry and nucleic acid chemistry. Conventional process for synthesis of aryl phosphorous compounds requires expensive ligands. In addition these processes need to be carried out at high temperature, are time consuming and requires more than one reactor. CSIR-NCL has developed a cost effective process that overcomes these processes for the synthesis of aryl phosphorous compounds. This process is a one pot, transition metal free reaction and can be carried out at room temperature. |
| Advantages | - Raw materials required for process are commercially available and inexpensive - All successive chemical reactions are carried out in one reactor - Process can be carried out at room temperature - The process is useful in generating chiral phosphine oxides under mild conditions that can serve as precursors to obtain novel aryl-phosphine ligands useful in organic synthesis |
| Knowhow is listed under following categories | |
| Knowhow from | CSIR-NCL, Pune |
| Scientific/ engineering subject areas | Chemical sciences & engineering |
| Investor interest categories | Others |
| Industries | Organic Chemicals, Fine Chemicals, Intermediates, Feedstocks |
| Customer categories and nature of business | Businesses and other industries (B2B) |
| Technology readiness levels | TRL C: Prototype developed and tested; technology demonstrated at pilot scale |
Year of development | 2013 |
| Whether patents are part of this offering ? | Yes |
| Related documents: | |
| Published Patents | |
| Publications | |
| Database reference | |
| Database record number | 20140423121322 |
| Date of upload | 23 / Apr / 2014 |
| Date of update | 23 / Apr / 2014 |
| URL to site when communicating about this knowhow | http://nclinnovations.org/khdb/viewrecord.php?recordno=20140423121322 |
| Request for this technology | Click here for Request Form |
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