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| Knowhow offering | |
| Title | An efficient and simple process for preparation of arylsulfones (used as building block for various drugs) |
| Knowhow is available for | A simple, one step process for the synthesis of aryl sulfones which is an important building block in organic chemistry and medicinal chemistry |
| Summary | Arylsulfones are widely used as building blocks for various drugs, such as Vioxx and Laropiprant. It has also been shown to exhibit antitumor activities and inhibit HIV-1 reverse transcriptase. Considering this interest in arylsulfones, CSIR-NCL has developed simple, one step, transition metal free process for synthesis of arylsulfones. This high yielding process can be conducted at room temperature. |
| Advantages | - This process is transition metal free and works at mild condition - Process requires very simple reagents, no need of activated aryl compound - The process is simple, one step and can conducted at room temperature and results in high yield of final product |
| Knowhow is listed under following categories | |
| Knowhow from | CSIR-NCL, Pune |
| Scientific/ engineering subject areas | Chemical sciences & engineering |
| Investor interest categories | Biotechnology/ Biomedical/ Health Technologies |
| Industries | Organic Chemicals, Fine Chemicals, Intermediates, Feedstocks |
| Customer categories and nature of business | Businesses and other industries (B2B) |
| Technology readiness levels | TRL C: Prototype developed and tested; technology demonstrated at pilot scale |
Year of development | 2013 |
| Whether patents are part of this offering ? | Yes |
| Related documents: | |
| Published Patents | |
| Database reference | |
| Database record number | 20140423024435 |
| Date of upload | 23 / Apr / 2014 |
| Date of update | 23 / Apr / 2014 |
| URL to site when communicating about this knowhow | http://nclinnovations.org/khdb/viewrecord.php?recordno=20140423024435 |
| Request for this technology | Click here for Request Form |
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