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| Knowhow offering | |
| Title | Novel silica based substrate (SBA-15) for efficient small molecules analysis in mass spectrometry |
| Knowhow is available for | Mesoporous silica (SBA-15) based substrate that enables efficient and selective analysis of small molecules from a complex mixture that contains both small and large molecules, using mass spectrometry. |
| Summary | Scientists from NCL and JNU have developed a platform which utilizes mesoporous silica (SBA-15) for use in laser desorption ionization mass spectrometry (LDI MS). This platform selectively excludes the detection of peptides, proteins and similar larger entities, allowing only the detection of small molecules quantitatively. This has been demonstrated on numerous classes of small molecules and from sample sources such as food, microbial cultures, biofluids from humans and synthetic molecules. |
| Advantages | • Selective detection of small molecules without any chromatographic separation from a complex sample source. • Can be used for detection and quantitative analysis of multiple trace components. • Negligible sample preparation required – thus reducing analysis time and cost. • This method can be adapted for high throughput analysis workflows. • Additional features could be incorporated by manipulating the substrate chemistry – opening up new applications. • Uses easily available raw materials – leading to viable process scalability |
| Knowhow is listed under following categories | |
| Knowhow from | CSIR-NCL, Pune |
| Scientific/ engineering subject areas | Life sciences/ biosciences & engineering ; Others |
| Investor interest categories | Materials Technology including Nanotechnology ; Others |
| Industries | Computing & Electronic Devices, Instrumentation ; Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics Others |
| Customer categories and nature of business | Businesses and other industries (B2B) ; Others |
| Technology readiness levels | TRL B: Proof-of-concept demonstrated in lab scale |
Year of development | 2009 |
| Whether patents are part of this offering ? | Yes |
| Related documents: | |
| Published Patents | |
| Write- ups and marketing documents | |
| Database reference | |
| Database record number | 20131003044724 |
| Date of upload | 3 / Oct / 2013 |
| Date of update | 4 / Oct / 2013 |
| URL to site when communicating about this knowhow | http://nclinnovations.org/khdb/viewrecord.php?recordno=20131003044724 |
| Request for this technology | Click here for Request Form |
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