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TitleSlow release hydrogel system for nutrient delivery to recombinant cell lines
Knowhow is available forSlow release polymer hydrogel system to feed nutrients to cell lines for optimal selection of high protein yielding recombinant cell lines
SummaryPolymer hydrogel mentioned can be used for slow/extended release (ranging over a period of 2-3 days to about 2 weeks) of nutrients to desired levels that can mimic fed batch conditions and hence used to identify more reliable clones and reducing the chance of failure at large-scale culture stage. These hydrogels could be used to release various nutrients like glucose, peptides, amino acids, nucleotides, etc.
Advantages• Nutrients of differing molecular weights (even lower) can be administered with controlled/slow/continuous release profiles • A short 2 step formation procedure • Non- cytotoxic; does not affect cell growth • Sterilizable by gamma irradiation • Usage leads to more reliable clone identification and less chance of failure at large scale culture stage

Knowhow is listed under following categories

Knowhow from
Scientific/ engineering subject areas Life sciences/ biosciences & engineering ; Chemical sciences & engineering
Investor interest categories Biotechnology/ Biomedical/ Health Technologies ; Materials Technology including Nanotechnology
Industries Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics ; Industrial Biotechnology Polymers, Plastics, Elastomers, Fibers, Adhesives, Paints, Specialty Polymers, Natural Polymers, Fibers and Leather Others
Customer categories and nature of business Businesses and other industries (B2B) ; Others
Technology readiness levels TRL B: Proof-of-concept demonstrated in lab scale

Year of development
Whether patents are part of this offering ?No

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Database reference

Database record number 20131002102724
Date of upload 3 / Oct / 2013
Date of update 4 / Oct / 2013
URL to site when communicating about this knowhow http://nclinnovations.org/khdb/viewrecord.php?recordno=20131002102724
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