Knowhow offering | |
Title | Process for the continuous flow synthesis of beta-amino crotonate (for use in anti-hypertensive drugs) |
Knowhow is available for | A process for continuous flow synthesis of >99.98% pure beta- amino crotonates which are intermediates to calcium channel blockers (anti-hypertensive drugs) |
Summary | A novel production process for beta-amino crotonate using a continuous mode reactor, with reduced reaction time, yet resulting in higher yield (>93%) and high-purity end-product (>99.98%). The process can be catalytic or catalysis- free : used to produce beta-amino crotonate and its analogues. |
Advantages | -Catalytic as well as catalysis-free, continuous process -Beta amino crotonate yielded is of high purity-process provides better control on product profile - Reduced reaction time - Can be prepared from a variety of amines and beta keto esters |
Knowhow is listed under following categories | |
Knowhow from | CSIR-NCL, Pune |
Scientific/ engineering subject areas | Chemical sciences & engineering ; Others |
Investor interest categories | Others ; Others |
Industries | Pharmaceuticals, Bulk Drugs, Formulations ; Others |
Customer categories and nature of business | Businesses and other industries (B2B) ; Others |
Technology readiness levels | TRL B: Proof-of-concept demonstrated in lab scale |
Year of development | 2010 |
Whether patents are part of this offering ? | Yes |
Related documents: | |
Published Patents | |
Write- ups and marketing documents | |
Database reference | |
Database record number | 20130930124812 |
Date of upload | 30 / Sep / 2013 |
Date of update | 19 / Feb / 2014 |
URL to site when communicating about this knowhow | http://nclinnovations.org/khdb/viewrecord.php?recordno=20130930124812 |
Request for this technology | Click here for Request Form |