Knowhow offering | |
Title | Continuous flow synthesis of sulphoxide compounds for use in drug formulations |
Knowhow is available for | A process for continuous flow synthesis of pharmaceutically important sulphoxide compounds (used as Proton Pump Inhibitors- used in treating gastric disorders) with very less reaction time and easy scalability |
Summary | Synthesis of sulphoxide compounds with reaction times of less than 1 minute. The reaction results in over 90% conversion and over 95% selectivity towards the target sulphoxide compounds (with less than 5% formation of undesired sulphone compounds) |
Advantages | -Process capable of easy scale up -Results in high yield of the product with 95% of selectivity towards the sulphoxide compounds -Conversion rate is > 90% -The process provides an alternative solvent (to chloroform, which is a volatile solvent that evaporates at room temperature and changes the reaction mass) |
Knowhow is listed under following categories | |
Knowhow from | CSIR-NCL, Pune |
Scientific/ engineering subject areas | Chemical sciences & engineering ; Others |
Investor interest categories | Biotechnology/ Biomedical/ Health Technologies ; Others |
Industries | Pharmaceuticals, Bulk Drugs, Formulations ; Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics Others |
Customer categories and nature of business | Businesses and other industries (B2B) ; Others |
Technology readiness levels | TRL B: Proof-of-concept demonstrated in lab scale |
Year of development | 2010 |
Whether patents are part of this offering ? | Yes |
Related documents: | |
Published Patents | |
Write- ups and marketing documents | |
Database reference | |
Database record number | 20130930122407 |
Date of upload | 30 / Sep / 2013 |
Date of update | 19 / Feb / 2014 |
URL to site when communicating about this knowhow | http://nclinnovations.org/khdb/viewrecord.php?recordno=20130930122407 |
Request for this technology | Click here for Request Form |