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Knowhow offering
Title	Continuous flow synthesis of sulphoxide compounds for use in drug formulations
Knowhow is available for	A process for continuous flow synthesis of pharmaceutically important sulphoxide compounds (used as Proton Pump Inhibitors- used in treating gastric disorders) with very less reaction time and easy scalability
Summary	Synthesis of sulphoxide compounds with reaction times of less than 1 minute. The reaction results in over 90% conversion and over 95% selectivity towards the target sulphoxide compounds (with less than 5% formation of undesired sulphone compounds)
Advantages	-Process capable of easy scale up -Results in high yield of the product with 95% of selectivity towards the sulphoxide compounds -Conversion rate is > 90% -The process provides an alternative solvent (to chloroform, which is a volatile solvent that evaporates at room temperature and changes the reaction mass)
Knowhow is listed under following categories
Knowhow from	CSIR-NCL, Pune
Scientific/ engineering subject areas	Chemical sciences & engineering ; Others
Investor interest categories	Biotechnology/ Biomedical/ Health Technologies ; Others
Industries	Pharmaceuticals, Bulk Drugs, Formulations ; Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics Others
Customer categories and nature of business	Businesses and other industries (B2B) ; Others
Technology readiness levels	TRL B: Proof-of-concept demonstrated in lab scale
Year of development	2010
Whether patents are part of this offering ?	Yes
Related documents:
Published Patents	PCTIN2010/000456
Write- ups and marketing documents	Tech Marketing Document
Database reference
Database record number	20130930122407
Date of upload	30 / Sep / 2013
Date of update	19 / Feb / 2014
URL to site when communicating about this knowhow	http://nclinnovations.org/khdb/viewrecord.php?recordno=20130930122407
Request for this technology	Click here for Request Form