Knowhow offering
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| Title | Nanoparticle-polymer complex for sustained release of oral care products |
| Knowhow is available for | A process for preparation of nanoparticle-polymer multilayer complexes for sustained release of active oral agents, which can anchor and retain on the surface enamel of the teeth, for extended periods of activity. |
| Summary | NCL scientists have developed a process for constructing nanoparticle-polymer complex for sustained release of active agents for oral care (for applications in toothpastes and oral rinses). Polymer multilayers are built up layer by layer on nanoparticles of 5-50 nm, consisting of a water repelling (hydrophobic) shell around a core of multiply (polyanion and polycation) charged material (the core can be of inorganics as silica, titania and/or clay) and encompassing outer layer with an affinity to the tooth enamel. |
| Advantages | • Precisely controlled polymer multilayers can be built on nanoparticles without the requirement of the cumbersome separation step after each coating of the polymer layers
• Active compounds localised as per the requirement by fine tuning the outer layer of the complexes- retained in the complex despite extensive rinsing with water
• Enables designing systems that can anchor and retain on the surface enamel of the teeth for extended periods by adjusting the ionic strengths
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Knowhow is listed under following categories
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Knowhow from
| CSIR-NCL, Pune |
| Scientific/ engineering subject areas |
Chemical sciences & engineering ; Others |
| Investor interest categories |
Materials Technology including Nanotechnology ; Others |
| Industries |
Surfactants, Detergents, FMCG ; |