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| Knowhow offering | |
| Title | Nanoparticle-polymer complex for sustained release of oral care products |
| Knowhow is available for | A process for preparation of nanoparticle-polymer multilayer complexes for sustained release of active oral agents, which can anchor and retain on the surface enamel of the teeth, for extended periods of activity. |
| Summary | NCL scientists have developed a process for constructing nanoparticle-polymer complex for sustained release of active agents for oral care (for applications in toothpastes and oral rinses). Polymer multilayers are built up layer by layer on nanoparticles of 5-50 nm, consisting of a water repelling (hydrophobic) shell around a core of multiply (polyanion and polycation) charged material (the core can be of inorganics as silica, titania and/or clay) and encompassing outer layer with an affinity to the tooth enamel. |
| Advantages | • Precisely controlled polymer multilayers can be built on nanoparticles without the requirement of the cumbersome separation step after each coating of the polymer layers • Active compounds localised as per the requirement by fine tuning the outer layer of the complexes- retained in the complex despite extensive rinsing with water • Enables designing systems that can anchor and retain on the surface enamel of the teeth for extended periods by adjusting the ionic strengths |
| Knowhow is listed under following categories | |
| Knowhow from | CSIR-NCL, Pune |
| Scientific/ engineering subject areas | Chemical sciences & engineering ; Others |
| Investor interest categories | Materials Technology including Nanotechnology ; Others |
| Industries | Surfactants, Detergents, FMCG ; Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics Others |
| Customer categories and nature of business | Businesses and other industries (B2B) ; Others |
| Technology readiness levels | TRL B: Proof-of-concept demonstrated in lab scale |
Year of development | 2007 |
| Whether patents are part of this offering ? | Yes |
| Related documents: | |
| Published Patents | |
| Write- ups and marketing documents | |
| Database reference | |
| Database record number | 20130929115539 |
| Date of upload | 30 / Sep / 2013 |
| Date of update | 4 / Oct / 2013 |
| URL to site when communicating about this knowhow | http://nclinnovations.org/khdb/viewrecord.php?recordno=20130929115539 |
| Request for this technology | Click here for Request Form |
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