Home > Details view

Details view

Knowhow offering

TitleA library of new small molecules that could be used as anticancer, antiviral drugs
Knowhow is available forA synthetic routine that allows one to manipulate the substrate flexibility at the final/penultimate steps- yielding a small library of modified nucleosides without the need for synthesising every compound from the beginning, and hence siginificantly reducing drug development time and costs.
SummaryNCL’s technology provides a strategy that allows synthesizing spironucleosides with enormous flexibility to modulate the substituents and properties of the resulting compounds at the final/penultimate steps. The provision to manipulate the substrate flexibility allows this approach to yield a small library of modified nucleosides without synthesizing every compound from the beginning.
Advantages• Cycloaddition process used is of high synthetic efficiency • These libraries significantly reduce drug development time and efforts • Good yield in the presence of the recommended catalysts • Easy and flexible penultimate bicycloannulation step involved

Knowhow is listed under following categories

Knowhow from
Scientific/ engineering subject areas Chemical sciences & engineering ; Life sciences/ biosciences & engineering
Investor interest categories Materials Technology including Nanotechnology ; Biotechnology/ Biomedical/ Health Technologies
Industries Pharmaceuticals, Bulk Drugs, Formulations ; Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics Others
Customer categories and nature of business Consumers (B2C) ; Others
Technology readiness levels TRL B: Proof-of-concept demonstrated in lab scale

Year of development
Whether patents are part of this offering ?Yes

Related documents:

Write- ups and marketing documents

Database reference

Database record number 20130929113120
Date of upload 30 / Sep / 2013
Date of update 4 / Oct / 2013
URL to site when communicating about this knowhow http://nclinnovations.org/khdb/viewrecord.php?recordno=20130929113120
Request for this technology Click here for Request Form


Technology provider:
Innovation Management partner:
Incubation partner: