{"id":950,"date":"2021-04-29T05:36:52","date_gmt":"2021-04-29T05:36:52","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=950"},"modified":"2021-04-29T05:36:52","modified_gmt":"2021-04-29T05:36:52","slug":"02-apr-2021-corticosteroids-not-associated-with-a-difference-in-hospital-mortality-for-patients-with-osci-3-5","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/02-apr-2021-corticosteroids-not-associated-with-a-difference-in-hospital-mortality-for-patients-with-osci-3-5\/","title":{"rendered":"(02 Apr 2021) Corticosteroids- not associated with a difference in hospital mortality for patients with OSCI 3-5"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p>Effect of corticosteroids on mortality in hospitalized COVID-19 patients not receiving invasive mechanical ventilation<\/p>\n<p>https:\/\/doi.org\/10.1002\/cpt.2245<\/p>\n<p class=\"\">Aim of this observational, single centre, prospective study was to assess the association between corticosteroids and hospital mortality in COVID-19 patients who did not receive IMV (OSCI 3-5). 1311 COVID-19 patients admitted to non-intensive care wards were included, and were divided in two cohorts: 1) 480 patients who received corticosteroid therapy 2) 831 patients who did not. The median daily dose was of 8 mg of dexamethasone or equivalent, with a mean therapy duration of 5 (3-9) days. The indication to administer or withhold corticosteroids was given by the treating physician. In-hospital mortality was similar between the two cohorts after adjusting for possible confounders.(ORadj 1.04, 95%CI 0.81-1.34, p=0.74). There was also no difference in Intensive Care Unit (ICU) admission (ORadj 0.81, 95% CI 0.56-1.17, p=0.26). COVID-19 patients with non-invasive mechanical ventilation (NIMV) had a lower risk for ICU admission if they received steroid therapy (ORadj 0.58, 95% CI 0.35-0.94, p=0.03). In conclusion, corticosteroids were overall not associated with a difference in hospital mortality for patients with COVID-19 with OSCI 3-5.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Effect of corticosteroids on mortality in hospitalized COVID-19 patients not receiving invasive mechanical ventilation https:\/\/doi.org\/10.1002\/cpt.2245 Aim of this observational, single centre, prospective study was to assess the association between corticosteroids and hospital mortality in COVID-19 patients who did not receive&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/02-apr-2021-corticosteroids-not-associated-with-a-difference-in-hospital-mortality-for-patients-with-osci-3-5\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(02 Apr 2021) Corticosteroids- not associated with a difference in hospital mortality for patients with OSCI 3-5&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[51,4],"tags":[52],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/950"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=950"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/950\/revisions"}],"predecessor-version":[{"id":951,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/950\/revisions\/951"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=950"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=950"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=950"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}