{"id":902,"date":"2021-04-07T05:59:11","date_gmt":"2021-04-07T05:59:11","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=902"},"modified":"2021-04-07T05:59:11","modified_gmt":"2021-04-07T05:59:11","slug":"10-mar-2021-remdesivir-no-positive-effect-on-clinical-outcomes","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/10-mar-2021-remdesivir-no-positive-effect-on-clinical-outcomes\/","title":{"rendered":"(10 Mar 2021) Remdesivir- no positive effect on clinical outcomes"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p id=\"page-title\" class=\"highwire-cite-title\">Efficacy of remdesivir in Japanese patients hospitalised with COVID-19: A large observational study using the COVID-19 Registry Japan<\/p>\n<p>https:\/\/www.medrxiv.org\/content\/10.1101\/2021.03.09.21253183v1<\/p>\n<div id=\"sec-3\" class=\"subsection\">\n<p id=\"p-4\" class=\"\">In total, 1907 of 15,225 patients met our inclusion criteria. After PS matching, 74 patients were assigned to the remdesivir case group and 195 patients to the non-remdesivir control group. In a PS-matched cohort, fatality risk (12.2% vs 13.3%;&nbsp;<em>P<\/em>&nbsp;= 1.0); risk of IMV\/ECMO (5.4% vs 4.6%;&nbsp;<em>P<\/em>&nbsp;= 0.757); length of intensive care unit stay (6 vs 6 days;&nbsp;<em>P<\/em>&nbsp;= 0.473) and length of IMV (13 vs 5 days;&nbsp;<em>P<\/em>&nbsp;= 0.509) were not different between the case and control groups. LoS in the case group was longer than in the control group (14 vs 11 days;&nbsp;<em>P<\/em> &lt; 0.001). This study suggested that remdesivir may have no positive effect on clinical outcomes and reductions in invasive\/non-invasive respiratory support for patients with COVID-19 in Japan.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Efficacy of remdesivir in Japanese patients hospitalised with COVID-19: A large observational study using the COVID-19 Registry Japan https:\/\/www.medrxiv.org\/content\/10.1101\/2021.03.09.21253183v1 In total, 1907 of 15,225 patients met our inclusion criteria. After PS matching, 74 patients were assigned to the remdesivir case&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/10-mar-2021-remdesivir-no-positive-effect-on-clinical-outcomes\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(10 Mar 2021) Remdesivir- no positive effect on clinical outcomes&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[4,5],"tags":[25],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/902"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=902"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/902\/revisions"}],"predecessor-version":[{"id":903,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/902\/revisions\/903"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=902"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=902"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=902"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}