{"id":879,"date":"2021-03-01T06:44:11","date_gmt":"2021-03-01T06:44:11","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=879"},"modified":"2021-03-01T06:44:11","modified_gmt":"2021-03-01T06:44:11","slug":"25-feb-2021-acei-arb-showed-a-beneficial-effect-on-mortality","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/25-feb-2021-acei-arb-showed-a-beneficial-effect-on-mortality\/","title":{"rendered":"(25 Feb 2021) ACEI\/ARB- showed a beneficial effect on mortality"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p id=\"page-title\" class=\"highwire-cite-title\">Effect of in-hospital treatment with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on mortality and complications in patients hospitalized for COVID-19: a large Spanish cohort study<\/p>\n<p>https:\/\/www.medrxiv.org\/content\/10.1101\/2021.02.24.21252391v1<\/p>\n<div id=\"sec-3\" class=\"subsection\">\n<p id=\"p-6\" class=\"\">Between February and June 2020, 11,205 patients were included, with mean age 67 years (SD=16.3) and 43.1% female; 2,162 patients received ACEI\/ARB treatment. ACEI\/ARB treatment showed a protective effect on all-cause mortality (<em>p<\/em>&lt;.0001). In hypertensive patients it was also protective in terms of IMV, ICU admission, and the composite outcome of prognosis (<em>p<\/em>&lt;.0001 for all). No differences were found in incidence of MACE. Patients previously treated with ACEI\/ARB who continued treatment during hospitalization had a lower incidence of the composite outcome of prognosis than those whose treatment was withdrawn (RR 0.67, 95%CI 0.63-0.76). ARB had a more beneficial effect on survival than ACEI (HR 0.77, 95%CI 0.62-0.96). ACEI\/ARB treatment during COVID-19 hospitalization had a protective effect on mortality. The benefits were greater in hypertensive patients, those who continued treatment during hospitalization, and those taking ARB.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Effect of in-hospital treatment with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on mortality and complications in patients hospitalized for COVID-19: a large Spanish cohort study https:\/\/www.medrxiv.org\/content\/10.1101\/2021.02.24.21252391v1 Between February and June 2020, 11,205 patients were included, with mean age&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/25-feb-2021-acei-arb-showed-a-beneficial-effect-on-mortality\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(25 Feb 2021) ACEI\/ARB- showed a beneficial effect on mortality&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[70,4],"tags":[75],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/879"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=879"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/879\/revisions"}],"predecessor-version":[{"id":880,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/879\/revisions\/880"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=879"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=879"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=879"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}