{"id":759,"date":"2021-01-11T12:02:27","date_gmt":"2021-01-11T12:02:27","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=759"},"modified":"2021-01-11T12:48:00","modified_gmt":"2021-01-11T12:48:00","slug":"06-jan-2021-corticosteroids-early-use-in-critically-ill-patients-associated-with-lower-mortality","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/06-jan-2021-corticosteroids-early-use-in-critically-ill-patients-associated-with-lower-mortality\/","title":{"rendered":"(06 Jan 2021) Corticosteroids- early use in critically ill patients associated with lower mortality"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p class=\"\">Early corticosteroids are associated with lower mortality in critically ill patients with COVID-19: a cohort study<\/p>\n<p class=\"\">https:\/\/doi.org\/10.1186\/s13054-020-03422-3<\/p>\n<div _ngcontent-hbb-c4=\"\" class=\"content\">This is a nationwide, prospective, multicenter, observational, cohort study in critically ill adult patients with COVID-19 admitted into Intensive Care Units (ICU) in Spain from 12th March to 29th June 2020. A total of 691 patients out of 882 (78.3%) received corticosteroid during their hospital stay. Patients treated with early-corticosteroids (n = 485) had lower ICU mortality (30.3% vs. never 36.6% and delayed 44.2%) and lower 7-day mortality (7.2% vs. never 15.2%) compared to non-early treated patients. They also had higher number of ventilator-free days, less length of ICU stay, and less secondary infections than delayed treated patients. There were no differences in medical complications between groups. Of note, early use of moderate-to-high doses was associated with better outcomes than low dose regimens.&nbsp; Early use of corticosteroids in critically ill patients with COVID-19 is associated with lower mortality than no or delayed use, and fewer complications than delayed use.<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Early corticosteroids are associated with lower mortality in critically ill patients with COVID-19: a cohort study https:\/\/doi.org\/10.1186\/s13054-020-03422-3 This is a nationwide, prospective, multicenter, observational, cohort study in critically ill adult patients with COVID-19 admitted into Intensive Care Units (ICU) in&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/06-jan-2021-corticosteroids-early-use-in-critically-ill-patients-associated-with-lower-mortality\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(06 Jan 2021) Corticosteroids- early use in critically ill patients associated with lower mortality&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[51,4],"tags":[52],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/759"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=759"}],"version-history":[{"count":3,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/759\/revisions"}],"predecessor-version":[{"id":762,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/759\/revisions\/762"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=759"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=759"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=759"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}