{"id":618,"date":"2020-10-31T07:13:15","date_gmt":"2020-10-31T07:13:15","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=618"},"modified":"2020-10-31T07:13:15","modified_gmt":"2020-10-31T07:13:15","slug":"29-oct-2020-hydroxychloroquine-no-benefit-in-viral-load-reduction","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/29-oct-2020-hydroxychloroquine-no-benefit-in-viral-load-reduction\/","title":{"rendered":"(29 Oct 2020) Hydroxychloroquine- no benefit in viral load reduction"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p class=\"\">No benefit of hydroxychloroquine on SARS-CoV-2 viral load reduction in non-critical hospitalized patients with COVID-19<\/p>\n<p class=\"\">https:\/\/doi.org\/10.1007\/s42770-020-00395-x<\/p>\n<p class=\"\">This prospective study comprised consecutive viral load measurements in patients with COVID-19 hospitalized with a moderate illness. Patients received 400 mg of HCQ every 12 h for 10 days according to the medical decision. Nasal swab samples were collected from patients during early, intermediary, and final clinical stage of COVID-19. A total of 155 samples were collected from 66 patients with COVID-19 (60% female), with a median age of 58 years. The viral load between studied groups, assumed as a semiquantitative measure of cycle threshold (Ct) values, presented no significant difference within the three consecutive measures (DeltaCt) (p &gt; 0.05). We also analyzed the DeltaCt viral load at different intervals of sample collection (Deltat &lt; 7; 7-12; and &gt; 12 days) without significant differences at any DeltaCt (p &gt; 0.05). In this study, we did not observe any change in viral load reduction in vivo with the use of HCQ.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>No benefit of hydroxychloroquine on SARS-CoV-2 viral load reduction in non-critical hospitalized patients with COVID-19 https:\/\/doi.org\/10.1007\/s42770-020-00395-x This prospective study comprised consecutive viral load measurements in patients with COVID-19 hospitalized with a moderate illness. Patients received 400 mg of HCQ every&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/29-oct-2020-hydroxychloroquine-no-benefit-in-viral-load-reduction\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(29 Oct 2020) Hydroxychloroquine- no benefit in viral load reduction&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[4,9],"tags":[10],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/618"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=618"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/618\/revisions"}],"predecessor-version":[{"id":619,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/618\/revisions\/619"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=618"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=618"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=618"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}