{"id":554,"date":"2020-09-26T12:12:41","date_gmt":"2020-09-26T12:12:41","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=554"},"modified":"2020-09-26T12:12:41","modified_gmt":"2020-09-26T12:12:41","slug":"25-sep-2020-corticosteroids-less-mortality-in-severe-patients-compared-to-critical-patients","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/25-sep-2020-corticosteroids-less-mortality-in-severe-patients-compared-to-critical-patients\/","title":{"rendered":"(25 Sep 2020) Corticosteroids- less mortality in severe patients compared to critical patients"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p class=\"\">Efficacy of corticosteroid treatment for hospitalized patients with severe COVID-19: a multicenter study.<\/p>\n<p>https:\/\/doi.org\/10.1016\/j.cmi.2020.09.014<\/p>\n<div _ngcontent-yur-c4=\"\" class=\"content\">Of 1717 patients with COVID-19 evaluated, 513 patients were included in the study; of these 170 (33%) were treated with corticosteroids. During the hospitalization 166 (34%) patients reached the primary outcome [60\/170 (35%) in the corticosteroid group and 106\/343 (31%) in the non-corticosteroid group]. At multivariable analysis corticosteroid treatment was not associated with lower 30-day mortality rate [aOR 0.59 (0.20-1.74), p=0.33]. After inverse probability of treatment weighting, corticosteroids were not associated to lower 30-day mortality [average treatment effect 0.05 (95% -0.02 to 0.09), p=0.12]. However, subgroup analysis revealed that in patients with PO2\/FiO2 &lt; 200 mmHg at admission [135 patients, 52 (38%) treated with corticosteroids] corticosteroid treatment was associated to a lower risk of 30-day mortality [23\/52 (44%) vs 45\/83 (54%), aOR 0.20 (95%CI 0.04 to 0.90), p=0.036]. Our study shows that the effect of corticosteroid treatment on mortality might be limited to critically ill COVID-19 patients.<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Efficacy of corticosteroid treatment for hospitalized patients with severe COVID-19: a multicenter study. https:\/\/doi.org\/10.1016\/j.cmi.2020.09.014 Of 1717 patients with COVID-19 evaluated, 513 patients were included in the study; of these 170 (33%) were treated with corticosteroids. During the hospitalization 166 (34%)&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/25-sep-2020-corticosteroids-less-mortality-in-severe-patients-compared-to-critical-patients\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(25 Sep 2020) Corticosteroids- less mortality in severe patients compared to critical patients&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[51,4],"tags":[52],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/554"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=554"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/554\/revisions"}],"predecessor-version":[{"id":555,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/554\/revisions\/555"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=554"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=554"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=554"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}