{"id":545,"date":"2020-09-19T11:39:12","date_gmt":"2020-09-19T11:39:12","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=545"},"modified":"2020-09-19T11:39:12","modified_gmt":"2020-09-19T11:39:12","slug":"18-sep-2020-corticosteroids-not-beneficial-at-later-stage-in-old-population","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/18-sep-2020-corticosteroids-not-beneficial-at-later-stage-in-old-population\/","title":{"rendered":"(18 Sep 2020) Corticosteroids- not beneficial at later stage in old population"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p id=\"page-title\" class=\"highwire-cite-title\">Association between corticosteroids and intubation or death among patients with COVID-19 pneumonia in non-ICU settings: an observational study using of real-world data from 51 hospitals in France and Luxembourg<\/p>\n<p>https:\/\/www.medrxiv.org\/content\/10.1101\/2020.09.16.20195750v1<\/p>\n<p class=\"\">Among the 891 patients included in the analysis, 203 were assigned to the CTC group. At day 28, corticosteroids did not reduce the rate of the primary outcome (wHR 0.92, 95% CI 0.61 to 1.39) nor the cumulative death rate (wHR 1.03, 95% CI 0.54 to 1.98). Corticosteroids significantly reduced the rate of the primary outcome for patients requiring oxygen \u2265 at 3L\/min (wHR 0.50, 95% CI 0.30 to 0.85) or C-Reactive Protein (CRP) \u2265 100mg\/L (wHR 0.44, 95%CI 0.23 to 0.85). We found a higher number of hyperglycaemia events among patients who received corticosteroids, but number of infections were similar across the two groups. We found no association between the use of corticosteroids and intubation or death in the broad population of patients \u226480 years old with COVID-19 hospitalized in non-ICU settings. However, the treatment was beneficial for patients with \u2265 3L\/min oxygen or CRP \u2265 100mg\/L at baseline. These data support the need to confirm the right timing of corticosteroids for patients with mild COVID.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Association between corticosteroids and intubation or death among patients with COVID-19 pneumonia in non-ICU settings: an observational study using of real-world data from 51 hospitals in France and Luxembourg https:\/\/www.medrxiv.org\/content\/10.1101\/2020.09.16.20195750v1 Among the 891 patients included in the analysis, 203 were&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/18-sep-2020-corticosteroids-not-beneficial-at-later-stage-in-old-population\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(18 Sep 2020) Corticosteroids- not beneficial at later stage in old population&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[51,4],"tags":[52],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/545"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=545"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/545\/revisions"}],"predecessor-version":[{"id":546,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/545\/revisions\/546"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=545"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=545"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=545"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}