{"id":543,"date":"2020-09-17T05:30:22","date_gmt":"2020-09-17T05:30:22","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=543"},"modified":"2020-09-17T06:30:58","modified_gmt":"2020-09-17T06:30:58","slug":"14-sep-2020-heparin-associated-with-a-clinically-significant-improvement-in-a-line-patency-duration","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/14-sep-2020-heparin-associated-with-a-clinically-significant-improvement-in-a-line-patency-duration\/","title":{"rendered":"(14 Sep 2020) Heparin- associated with a clinically significant improvement in a-line patency duration"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p>A low dose heparinized saline protocol is associated with improved duration of arterial line patency in critically ill COVID-19 patients<\/p>\n<p>https:\/\/doi.org\/10.1016\/j.jcrc.2020.08.025<\/p>\n<div _ngcontent-ltp-c4=\"\" class=\"content\">In this observational cohort study, patients &gt;\/=18 years with COVID-19 admitted to an ICU at one institution from March 20-May 25, 2020 were divided into two cohorts. Pre-LDHS patients had an episode of a-line thrombosis between March 20-April 19. Post-LDHS patients had an episode of a-line thrombosis between April 20-May 25 and received an LDHS solution (10 units\/h) through their a-line pressure bag. Forty-one patients (pre-LDHS) and 30 patients (post-LDHS) were identified. Baseline characteristics were similar between groups, including age (61 versus 54 years; p = 0.24), median Sequential Organ Failure Assessment score (6 versus 7; p = 0.67) and systemic anticoagulation (47% versus 32%; p = 0.32). Median duration of a-line patency was significantly longer in post-LDHS versus pre-LDHS patients (8.5 versus 2.9 days; p &lt; 0.001). The incidence of bleeding complications was similar between cohorts (13% vs. 10%; p = 0.71). A LDHS protocol was associated with a clinically significant improvement in a-line patency duration in COVID-19 patients, without increased bleeding risk.<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A low dose heparinized saline protocol is associated with improved duration of arterial line patency in critically ill COVID-19 patients https:\/\/doi.org\/10.1016\/j.jcrc.2020.08.025 In this observational cohort study, patients &gt;\/=18 years with COVID-19 admitted to an ICU at one institution from March&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/14-sep-2020-heparin-associated-with-a-clinically-significant-improvement-in-a-line-patency-duration\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(14 Sep 2020) Heparin- associated with a clinically significant improvement in a-line patency duration&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[4,64],"tags":[65],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/543"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=543"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/543\/revisions"}],"predecessor-version":[{"id":544,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/543\/revisions\/544"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=543"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=543"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=543"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}