{"id":503,"date":"2020-08-31T10:09:55","date_gmt":"2020-08-31T10:09:55","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=503"},"modified":"2020-08-31T10:09:55","modified_gmt":"2020-08-31T10:09:55","slug":"30-august-2020-tocilizumab-improvement-in-oxygenation-was-observed-in-80-n16-of-the-patients-by7-days","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/30-august-2020-tocilizumab-improvement-in-oxygenation-was-observed-in-80-n16-of-the-patients-by7-days\/","title":{"rendered":"(30 August 2020) Tocilizumab- improvement in oxygenation was observed in 80% (n=16) of the patients by7 days"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p>Tocilizumab use in COVID -19 associated pneumonia<\/p>\n<p>https:\/\/doi.org\/10.1002\/jmv.26471<\/p>\n<p class=\"\">Out of 77 patients who received TCB in addition to standard of care, 34% (n=26) received TCB within 48 hours of admission. One-to-two propensity matching identified 20 vs. 40 patients in the TCB and no-TCB treatment arms. In the TCB group, an improvement in oxygenation was observed in 80% (n=16) of the patients by 7 days post TCB administration. After matching, there was no difference in clinical outcomes between TCB and no-TCB patients. In-hospital death: 10% vs. 8%; p=0.823, Septic Shock: 10% vs 11%, p=0.912, AKI requiring hemodialysis (10% vs. 13%; p=0.734). Early treatment with TCB in patients admitted for COVID -19 led to an improvement in their oxygen status during hospitalization. This change however did not translate into improved survival when compared to a matched cohort with a similar clinical profile.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Tocilizumab use in COVID -19 associated pneumonia https:\/\/doi.org\/10.1002\/jmv.26471 Out of 77 patients who received TCB in addition to standard of care, 34% (n=26) received TCB within 48 hours of admission. One-to-two propensity matching identified 20 vs. 40 patients in the&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/30-august-2020-tocilizumab-improvement-in-oxygenation-was-observed-in-80-n16-of-the-patients-by7-days\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(30 August 2020) Tocilizumab- improvement in oxygenation was observed in 80% (n=16) of the patients by7 days&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[4,18],"tags":[27],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/503"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=503"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/503\/revisions"}],"predecessor-version":[{"id":504,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/503\/revisions\/504"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=503"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=503"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=503"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}