{"id":449,"date":"2020-08-20T11:56:08","date_gmt":"2020-08-20T11:56:08","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=449"},"modified":"2020-08-20T11:56:08","modified_gmt":"2020-08-20T11:56:08","slug":"11-aug-2020-hydroxychloroquine-administration-in-critically-ill-patients-not-useful","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/11-aug-2020-hydroxychloroquine-administration-in-critically-ill-patients-not-useful\/","title":{"rendered":"(11 Aug 2020) Hydroxychloroquine- administration in critically ill patients not useful"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p><strong>Effects of Hydroxychloroquine on Covid-19 in Intensive Care Unit Patients: Preliminary Results<\/strong><\/p>\n<p><strong><a href=\"https:\/\/doi.org\/10.1016\/j.ijantimicag.2020.106136\">https:\/\/doi.org\/10.1016\/j.ijantimicag.2020.106136<\/a><\/strong><\/p>\n<p>A single-center retrospective study was performed from March to April 2020 in an ICU of a university hospital. All patients admitted to our ICU with a confirmed Covid-19 pneumonia and treated by hydroxychloroquine were included. We compared 17 patients in whom the hydroxychloroquine plasma concentration was in the therapeutic target (on-target) and 12 patients in whom the plasma concentration was below the target (off-target). The follow-up of patients was 15 days. No association was found between hydroxychloroquine plasma concentration and viral load evolution (p=0.77). There was no significant difference between the two groups for the duration of mechanical ventilation, length of ICU stay, in-hospital mortality, and 15-days mortality. This finding suggests that hydroxychloroquine administration for Covid-19 patients hospitalized in ICU is not associated with improved outcomes. These results need confirmation by larger multicenter studies.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Effects of Hydroxychloroquine on Covid-19 in Intensive Care Unit Patients: Preliminary Results https:\/\/doi.org\/10.1016\/j.ijantimicag.2020.106136 A single-center retrospective study was performed from March to April 2020 in an ICU of a university hospital. All patients admitted to our ICU with a confirmed&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/11-aug-2020-hydroxychloroquine-administration-in-critically-ill-patients-not-useful\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(11 Aug 2020) Hydroxychloroquine- administration in critically ill patients not useful&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[4,9,1],"tags":[10],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/449"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=449"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/449\/revisions"}],"predecessor-version":[{"id":450,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/449\/revisions\/450"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=449"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=449"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=449"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}