{"id":341,"date":"2020-07-06T06:52:14","date_gmt":"2020-07-06T06:52:14","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=341"},"modified":"2020-07-06T06:52:14","modified_gmt":"2020-07-06T06:52:14","slug":"03-july-2020-umifenovir-no-evidence-to-support-the-use-of-umifenovir-for-improving-patient-important-outcomes","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/03-july-2020-umifenovir-no-evidence-to-support-the-use-of-umifenovir-for-improving-patient-important-outcomes\/","title":{"rendered":"(03 July 2020) Umifenovir-no evidence to support the use of umifenovir for improving patient-important outcomes"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p>Efficacy and safety of umifenovir for coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis<\/p>\n<p>https:\/\/doi.org\/10.1002\/jmv.26256<\/p>\n<p>&nbsp;A total of 12 studies with 1052 patients&nbsp; were included in&nbsp; final review studies. Compared with control group, umifenovir is associated with higher negative rate of PCR on day 14 (RR:1.27; 95% CI: 1.04 to 1.55). However, umifenovir is not related to nucleus acid negative conversion time(MD: 0.09; 95% CI: -1.48 to 1.65), negative rate on day 7(RR:1.09; 95% CI: 0.91 to 1.31), incidence of composite endpoint (RR:1.20; 95% CI: 0.61 to 2.37), rate of fever alleviation on day 7 (RR:1.00; 95% CI: 0.91 to 1.10), rate of cough alleviation on day 7 (RR:1.00; 95% CI: 0.85 to 1.18), or hospital length of stay (LOS) (MD: 1.34; 95% CI: -2.08 to 4.76). Additionally, umifenovir was safe in COVID-19 patients (RR for incidence of adverse events:1.29; 95% CI: 0.57 to 2.92). The results of sensitivity analysis and subgroup analysis were similar to pooled results. There is no evidence to support the use of umifenovir for improving patient-important outcomes in patients with COVID-19.&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Efficacy and safety of umifenovir for coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis https:\/\/doi.org\/10.1002\/jmv.26256 &nbsp;A total of 12 studies with 1052 patients&nbsp; were included in&nbsp; final review studies. Compared with control group, umifenovir is associated with higher negative&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/03-july-2020-umifenovir-no-evidence-to-support-the-use-of-umifenovir-for-improving-patient-important-outcomes\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(03 July 2020) Umifenovir-no evidence to support the use of umifenovir for improving patient-important outcomes&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[4,15],"tags":[46],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/341"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=341"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/341\/revisions"}],"predecessor-version":[{"id":342,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/341\/revisions\/342"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=341"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=341"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=341"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}