{"id":188,"date":"2020-05-18T11:00:53","date_gmt":"2020-05-18T11:00:53","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=188"},"modified":"2020-05-18T11:00:53","modified_gmt":"2020-05-18T11:00:53","slug":"16-may-2020-hydroxychloroquine-no-evidence-for-negative-conversion-of-sars-cov-2","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/16-may-2020-hydroxychloroquine-no-evidence-for-negative-conversion-of-sars-cov-2\/","title":{"rendered":"(16 May 2020) Hydroxychloroquine- no evidence for negative conversion of SARS-CoV-2"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p id=\"page-title\" class=\"highwire-cite-title\">Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial<\/p>\n<p class=\"\">https:\/\/www.bmj.com\/content\/369\/bmj.m1849&nbsp;<\/p>\n<p class=\"\">This study (conducted during the outbreak of covid-19 in China -ChiCTR2000029868) is the first randomised controlled trial evaluating administration of hydroxychloroquine in patients with covid-19. The probability of negative conversion by 28 days in the standard of care plus hydroxychloroquine group was 85.4%&nbsp; similar to that in the standard of care group 81.3%.&nbsp; In the safety population, adverse events were recorded more in hydroxychloroquine recipients.The findings do not provide evidence to support an increase in the probability of negative conversion of SARS-CoV-2 conferred by the addition of hydroxychloroquine administration to the current standard of care in patients admitted to hospital with mainly persistent mild to moderate covid-19.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial https:\/\/www.bmj.com\/content\/369\/bmj.m1849&nbsp; This study (conducted during the outbreak of covid-19 in China -ChiCTR2000029868) is the first randomised controlled trial evaluating administration of hydroxychloroquine in patients&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/16-may-2020-hydroxychloroquine-no-evidence-for-negative-conversion-of-sars-cov-2\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(16 May 2020) Hydroxychloroquine- no evidence for negative conversion of SARS-CoV-2&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[4,9],"tags":[58],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/188"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=188"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/188\/revisions"}],"predecessor-version":[{"id":189,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/188\/revisions\/189"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=188"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=188"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=188"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}