{"id":1002,"date":"2021-04-30T14:54:33","date_gmt":"2021-04-30T14:54:33","guid":{"rendered":"https:\/\/nclinnovations.org\/covid19monitor\/?p=1002"},"modified":"2021-04-30T14:54:33","modified_gmt":"2021-04-30T14:54:33","slug":"25-apr-2021-dexamethasone-showed-better-survival-in-severe-covid-19-compared-to-tcz","status":"publish","type":"post","link":"https:\/\/nclinnovations.org\/covid19monitor\/25-apr-2021-dexamethasone-showed-better-survival-in-severe-covid-19-compared-to-tcz\/","title":{"rendered":"(25 Apr 2021) Dexamethasone- showed better survival in severe COVID-19 compared to TCZ"},"content":{"rendered":"<div class=\"boldgrid-section\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md-12 col-xs-12 col-sm-12\">\n<p class=\"\">Short term survival of critically ill COVID-19 Egyptian patients on assisted ventilation treated by either Dexamethasone or Tocilizumab<\/p>\n<p class=\"\">https:\/\/doi.org\/10.1038\/s41598-021-88086-x<\/p>\n<p class=\"\">109 critically ill COVID-19 patients randomly assigned to either TCZ therapy (46 patients) or pulse Dexamethasone therapy (63 patients). Kaplan-Meier survival analysis showed better survival in Dexamethasone group compared with TCZ (P = 0.002), patients didn&#8217;t need vasopressor at admission (P &lt; 0.0001), patients on non-invasive ventilation compared to patients on mechanical ventilation (P&lt;0.0001 ), and in patients with ground glass pattern in CT chest (P&lt;0.0001 ) compared with those who have consolidation. Cox regression analysis showed that, TCZ therapy (HR = 2.162, 95% CI, 1.144-4.087, P &lt;0.0001) compared with Dexamethasone group, higher neutrophil\/Lymphocyte ratio (HR = 2.40, CI, 1.351-4.185, P = 0.003), lower PaO2\/FiO2, 2 days after treatment, (HR = 1.147, 95% CI, 1.002-1.624, P &lt; 0.0001) independently predicted higher probability of mortality. Dexamethasone showed better survival in severe COVID-19 compared to TCZ. Considering the risk factors mentioned here is crucial when dealing with severe COVID-19 cases.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Short term survival of critically ill COVID-19 Egyptian patients on assisted ventilation treated by either Dexamethasone or Tocilizumab https:\/\/doi.org\/10.1038\/s41598-021-88086-x 109 critically ill COVID-19 patients randomly assigned to either TCZ therapy (46 patients) or pulse Dexamethasone therapy (63 patients). Kaplan-Meier survival&hellip; <span class=\"read-more-span\"><a href=\"https:\/\/nclinnovations.org\/covid19monitor\/25-apr-2021-dexamethasone-showed-better-survival-in-severe-covid-19-compared-to-tcz\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;(25 Apr 2021) Dexamethasone- showed better survival in severe COVID-19 compared to TCZ&#8221;<\/span> <span class=\"genericon genericon-next\"><\/span><\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bgseo_title":"","bgseo_description":"","bgseo_robots_index":"index","bgseo_robots_follow":"follow"},"categories":[81,4],"tags":[68],"_links":{"self":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/1002"}],"collection":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/comments?post=1002"}],"version-history":[{"count":1,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/1002\/revisions"}],"predecessor-version":[{"id":1003,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/posts\/1002\/revisions\/1003"}],"wp:attachment":[{"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/media?parent=1002"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/categories?post=1002"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nclinnovations.org\/covid19monitor\/wp-json\/wp\/v2\/tags?post=1002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}