Ivermectin, Drugs Monitor

(14 May 2021) Ivermectin, Doxycycline- number of patients with a

May 27, 2021

Ivermectin in combination with doxycycline for treating COVID-19 symptoms: a randomized trial https://doi.org/10.1177/03000605211013550 NCT04523831-This was a randomized, blinded, placebo-controlled trial in patients with mild-to-moderate COVID-19 symptoms randomly assigned to treatment (n = 200) and placebo (n = 200) groups. The… Continue reading "(14 May 2021) Ivermectin, Doxycycline- number of patients with a </=7-day recovery was 61% Vs 44% in placebo"

(06 May 2021) Ivermectin- the rate of clinical improvement was 73.3% Vs 53.3% in the control group

May 27, 2021

Evaluation of the effectiveness and safety of adding ivermectin to treatment in severe COVID-19 patients https://doi.org/10.1186/s12879-021-06104-9 NCT04646109-A total of 66 patients, 36 in the study group and 30 in the control group were included in the study. Mutations affecting ivermectin… Continue reading "(06 May 2021) Ivermectin- the rate of clinical improvement was 73.3% Vs 53.3% in the control group"

(18 Apr 2021) Ivermectin- a significant protection of Ivermectin as a PrEP method of infection from SARS-CoV-2 was observed

April 30, 2021

Retrospective cohort study of Ivermectin as a SARS-CoV-2 pre-exposure prophylaxis method in Healthcare Workers https://www.medrxiv.org/content/10.1101/2021.04.10.21255248v2 NCT04832945-The study began on June 29, 2020 and ended on July 26, 2020, where 713 active healthcare personnel were included for the analysis, of which… Continue reading "(18 Apr 2021) Ivermectin- a significant protection of Ivermectin as a PrEP method of infection from SARS-CoV-2 was observed"

(30 Mar 2021) Ivermectin- improved the clinical state even in the presence of comorbidities

April 7, 2021

IVERMECTIN REPROPOSING FOR COVID-19 TREATMENT OUTPATIENTS IN MILD STAGE IN PRIMARY HEALTH CARE CENTERS https://www.medrxiv.org/content/10.1101/2021.03.29.21254554v1 NCT04784481- A significant reduction in the symptom numbers was observed in the EG when the medical examination was performed from 5th to 9th days, after starting treatment… Continue reading "(30 Mar 2021) Ivermectin- improved the clinical state even in the presence of comorbidities"

(17 Mar 2021) Ivermectin- reduction in SARS-CoV-2 viral load within 7 days

April 7, 2021

Use of ivermectin in the treatment of Covid-19: A pilot trial https://doi.org/10.1016/j.toxrep.2021.03.003 NCT04431466- A total of 32 patients were enrolled and randomized to treatment. SOC treatment together with ivermectin did not result in any serious adverse events. All patients exhibited… Continue reading "(17 Mar 2021) Ivermectin- reduction in SARS-CoV-2 viral load within 7 days"

(23 Feb 2021) Ivermectin & Hydroxychloroquine- neither of them decreases the number of in-hospital days

March 1, 2021

Efficacy and safety of Ivermectin and Hydroxychloroquine in patients with severe COVID-19. A randomized controlled trial https://www.medrxiv.org/content/10.1101/2021.02.18.21252037v1 NCT04391127–During the month of August, the admission of patients requiring hospitalization mostly encompassed cases with severe respiratory failure, so we ended the recruitment… Continue reading "(23 Feb 2021) Ivermectin & Hydroxychloroquine- neither of them decreases the number of in-hospital days"

(19 Feb 2021) Ivermectin-Days to COVID negativity was significantly and dose dependently reduced by IV

March 1, 2021

Ivermectin shows clinical benefits in mild to moderate COVID19: A randomised controlled double-blind, dose-response study in Lagos https://doi.org/10.1093/qjmed/hcab035 We conducted a translational proof of concept (PoC) randomized, double blind placebo controlled, dose response, parallel group study of IV efficacy in… Continue reading "(19 Feb 2021) Ivermectin-Days to COVID negativity was significantly and dose dependently reduced by IV"

(17 Feb 2021) Ivermectin- associated with a 73% reduction of SARS-CoV-2 infection among healthcare workers

February 19, 2021

Role of ivermectin in the prevention of SARS-CoV-2 infection among healthcare workers in India: A matched case-control study https://doi.org/10.1371/journal.pone.0247163 Ivermectin prophylaxis was taken by 76 controls and 41 cases. Two-dose ivermectin prophylaxis (AOR 0.27, 95% CI, 0.15-0.51) was associated with… Continue reading "(17 Feb 2021) Ivermectin- associated with a 73% reduction of SARS-CoV-2 infection among healthcare workers"

(17 Feb 2021) Nitazoxanide, Ivermectin, Ribavirin- plus Zinc effectively clear the SARS-COV2 from nasopharynx

February 19, 2021

Effect of a combination of Nitazoxanide, Ribavirin and Ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID-19 https://doi.org/10.1002/jmv.26880 NCT04392427- This non-randomized controlled trial included 62 patients on triple combination treatment versus 51 age- and sex-matched patients on… Continue reading "(17 Feb 2021) Nitazoxanide, Ivermectin, Ribavirin- plus Zinc effectively clear the SARS-COV2 from nasopharynx"

(13 Feb 2021) TNR4 therapy- 75% and 81% lower risk of being hospitalized or death

February 16, 2021

Effectiveness of a multidrug therapy consisting of ivermectin, azithromycin, montelukast and acetylsalicylic acid to prevent hospitalization and death among ambulatory COVID-19 cases in Tlaxcala, Mexico https://doi.org/10.1016/j.ijid.2021.02.014 The aim of this study was to assess the effectiveness of a multidrug-therapy consisting… Continue reading "(13 Feb 2021) TNR4 therapy- 75% and 81% lower risk of being hospitalized or death"

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