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TitleAn efficient and simple process for preparation of arylsulfones (used as building block for various drugs)
Knowhow is available forA simple, one step process for the synthesis of aryl sulfones which is an important building block in organic chemistry and medicinal chemistry
SummaryArylsulfones are widely used as building blocks for various drugs, such as Vioxx and Laropiprant. It has also been shown to exhibit antitumor activities and inhibit HIV-1 reverse transcriptase. Considering this interest in arylsulfones, CSIR-NCL has developed simple, one step, transition metal free process for synthesis of arylsulfones. This high yielding process can be conducted at room temperature.
Advantages- This process is transition metal free and works at mild condition
- Process requires very simple reagents, no need of activated aryl compound
- The process is simple, one step and can conducted at room temperature and results in high yield of final product


Knowhow is listed under following categories

Knowhow from
CSIR-NCL, Pune
Scientific/ engineering subject areas Chemical sciences & engineering
Investor interest categories Biotechnology/ Biomedical/ Health Technologies
Industries Organic Chemicals, Fine Chemicals, Intermediates, Feedstocks
Customer categories and nature of business Businesses and other industries (B2B)
Technology readiness levels TRL C: Prototype developed and tested; technology demonstrated at pilot scale

Year of development
2013
Whether patents are part of this offering ?Yes


Related documents:

Published Patents


Database reference

Database record number 20140423024435
Date of upload 23 / Apr / 2014
Date of update 23 / Apr / 2014
URL to site when communicating about this knowhow http://nclinnovations.org/khdb/viewrecord.php?recordno=20140423024435
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