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| Knowhow offering | |
| Title | Slow release hydrogel system for nutrient delivery to recombinant cell lines |
| Knowhow is available for | Slow release polymer hydrogel system to feed nutrients to cell lines for optimal selection of high protein yielding recombinant cell lines |
| Summary | Polymer hydrogel mentioned can be used for slow/extended release (ranging over a period of 2-3 days to about 2 weeks) of nutrients to desired levels that can mimic fed batch conditions and hence used to identify more reliable clones and reducing the chance of failure at large-scale culture stage. These hydrogels could be used to release various nutrients like glucose, peptides, amino acids, nucleotides, etc. |
| Advantages | • Nutrients of differing molecular weights (even lower) can be administered with controlled/slow/continuous release profiles • A short 2 step formation procedure • Non- cytotoxic; does not affect cell growth • Sterilizable by gamma irradiation • Usage leads to more reliable clone identification and less chance of failure at large scale culture stage |
| Knowhow is listed under following categories | |
| Knowhow from | CSIR-NCL, Pune |
| Scientific/ engineering subject areas | Life sciences/ biosciences & engineering ; Chemical sciences & engineering |
| Investor interest categories | Biotechnology/ Biomedical/ Health Technologies ; Materials Technology including Nanotechnology |
| Industries | Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics ; Industrial Biotechnology Polymers, Plastics, Elastomers, Fibers, Adhesives, Paints, Specialty Polymers, Natural Polymers, Fibers and Leather Others |
| Customer categories and nature of business | Businesses and other industries (B2B) ; Others |
| Technology readiness levels | TRL B: Proof-of-concept demonstrated in lab scale |
Year of development | 2010 |
| Whether patents are part of this offering ? | No |
| Related documents: | |
| Publications | |
| Write- ups and marketing documents | |
| Database reference | |
| Database record number | 20131002102724 |
| Date of upload | 3 / Oct / 2013 |
| Date of update | 4 / Oct / 2013 |
| URL to site when communicating about this knowhow | http://nclinnovations.org/khdb/viewrecord.php?recordno=20131002102724 |
| Request for this technology | Click here for Request Form |
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