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TitleNanoparticle-polymer complex for sustained release of oral care products
Knowhow is available forA process for preparation of nanoparticle-polymer multilayer complexes for sustained release of active oral agents, which can anchor and retain on the surface enamel of the teeth, for extended periods of activity.
SummaryNCL scientists have developed a process for constructing nanoparticle-polymer complex for sustained release of active agents for oral care (for applications in toothpastes and oral rinses). Polymer multilayers are built up layer by layer on nanoparticles of 5-50 nm, consisting of a water repelling (hydrophobic) shell around a core of multiply (polyanion and polycation) charged material (the core can be of inorganics as silica, titania and/or clay) and encompassing outer layer with an affinity to the tooth enamel.
Advantages• Precisely controlled polymer multilayers can be built on nanoparticles without the requirement of the cumbersome separation step after each coating of the polymer layers • Active compounds localised as per the requirement by fine tuning the outer layer of the complexes- retained in the complex despite extensive rinsing with water • Enables designing systems that can anchor and retain on the surface enamel of the teeth for extended periods by adjusting the ionic strengths

Knowhow is listed under following categories

Knowhow from
Scientific/ engineering subject areas Chemical sciences & engineering ; Others
Investor interest categories Materials Technology including Nanotechnology ; Others
Industries Surfactants, Detergents, FMCG ; Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics Others
Customer categories and nature of business Businesses and other industries (B2B) ; Others
Technology readiness levels TRL B: Proof-of-concept demonstrated in lab scale

Year of development
Whether patents are part of this offering ?Yes

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Database reference

Database record number 20130929115539
Date of upload 30 / Sep / 2013
Date of update 4 / Oct / 2013
URL to site when communicating about this knowhow http://nclinnovations.org/khdb/viewrecord.php?recordno=20130929115539
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